How to Use a Unit Dose Pressure Roller

Quick answer

Use a unit dose pressure roller to firmly adhere cold seal cards to cold seal blisters, creating tamper-evident medication packages quickly and consistently.

Step-by-step sealing process

1. Prepare the blister and card: Place the cold seal blister face up on a flat surface. Align the cold seal card printed side up over the blister, ensuring the medication cavities are centered under the card. Misalignment is the most common mistake — check that the card covers all cavities before rolling.
2. Position the roller at the starting edge: Hold the pressure roller at a 45-degree angle and place it at one edge of the card. Apply moderate downward pressure and roll smoothly across the entire card in one continuous motion. Rolling too fast or with uneven pressure can create air bubbles or weak seals. Use a steady, deliberate pace.
3. Inspect the seal and repeat if needed: Lift the card gently to check that all edges and cavities are fully adhered. If you see lifted areas, reposition the roller and roll over those spots again with firm pressure. Do not over-roll — multiple passes may weaken the adhesive. One or two smooth passes are usually sufficient.

Product used in this guide

• Apothecary Products® Unit Dose Pressure Roller: The Apothecary Products Unit Dose Pressure Roller is designed to adhere Ezy Dose Cold Seal Cards to Cold Seal Blisters for accurate medication dosing. Using the correct roller ensures consistent seal pressure, reducing the risk of package failure and patient dose errors.